Basic Information
ID: ALA4770550
Type: Binding
Description: Agonist activity at 5HT7 receptor in C57BL/6 mouse hippocampal neurons assessed as reversal of DHPG induced mGluR-dependent long-term depression by measuring excitatory postsynaptic current at -70 mV holding potential at 100 nM pretreated with DHPG for 5 mins after DHPG washout compound addition measured after 40 mins by whole cell patch clamp assay (Rvb = 67.7 +/- 8 %)
Organism: Mus musculus
Strain: C57BL/6
Cell type: Neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA4770550
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.66 | 5.24 | 5.24 |
| 501.63 | 5.06 | 5.06 |