Basic Information
ID: ALA4770554
Type: Binding
Description: Selectivity index, ratio of Ki for displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells incubated for 60 mins by radioligand binding assay to Ki for displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells incubated for 60 mins by radioligand binding assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Unchecked(ALA612545)
Document: ALA4765335
Selectivity index, ratio of Ki for displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells incubated for 60 mins by radioligand binding assay to Ki for displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells incubated for 60 mins by radioligand binding assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4770554
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.00 | 6.14 | 6.14 |
| 469.00 | 6.14 | 6.14 |
| 533.67 | 6.30 | 6.30 |
| 441.58 | 5.22 | 5.22 |
| 443.55 | 3.80 | 3.80 |
| 534.66 | 5.24 | 5.24 |