Basic Information
ID: ALA4771188
Type: Binding
Description: Inhibition of N7-MTase activity of N-terminal His6-tagged SARS-CoV nsp14 expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate at 50 uM preincubated with enzyme followed by substrate addition and measured after 30 mins by filter binding assay
Organism: Severe acute respiratory syndrome-related coronavirus
Activity Charts
Bioactivity
Activity Types for Assay ALA4771188
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.39 | -2.06 | -2.06 |
| 677.72 | -0.98 | -0.98 |
| 659.66 | -2.66 | -2.66 |
| 660.65 | -3.81 | -3.81 |
| 774.73 | -2.31 | -2.31 |
| 734.15 | -1.57 | -1.57 |
| 684.11 | -0.76 | -0.76 |
| 674.68 | -3.72 | -3.72 |
| 645.63 | -2.75 | -2.75 |
| 659.66 | -4.41 | -4.41 |
| 615.65 | -1.81 | -1.81 |
| 779.15 | -1.66 | -1.66 |
| 729.11 | -0.85 | -0.85 |
| 744.70 | -2.32 | -2.32 |
| 774.73 | -2.31 | -2.31 |
| 812.70 | -1.30 | -1.30 |
| 559.54 | -3.32 | -3.32 |