Assay Report Card

Basic Information

ID: ALA4771189

Type: Binding

Description: Inhibition of N7-MTase activity of Vaccinia virus mRNA capping enzyme D1/D12 complex using GpppAC4 and [3H]SAM as substrate at 50 uM preincubated with enzyme followed by substrate addition and measured after 30 mins by filter binding assay

Organism: Vaccinia virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.39-2.06-2.06
677.72-0.98-0.98
659.66-2.66-2.66
660.65-3.81-3.81
774.73-2.31-2.31
734.15-1.57-1.57
684.11-0.76-0.76
674.68-3.72-3.72
645.63-2.75-2.75
659.66-4.41-4.41
615.65-1.81-1.81
779.15-1.66-1.66
729.11-0.85-0.85
744.70-2.32-2.32
774.73-2.31-2.31
812.70-1.30-1.30
559.54-3.32-3.32