Basic Information
ID: ALA4771192
Type: ADME
Description: Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme followed by substrate addition and measured after 30 mins by filter binding assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4771192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.39 | -2.06 | -2.06 |
| 677.72 | -0.98 | -0.98 |
| 660.65 | -3.81 | -3.81 |
| 774.73 | -2.31 | -2.31 |
| 734.15 | -1.57 | -1.57 |
| 684.11 | -0.76 | -0.76 |
| 779.15 | -1.66 | -1.66 |
| 744.70 | -2.32 | -2.32 |
| 774.73 | -2.31 | -2.31 |
| 812.70 | -1.30 | -1.30 |