Basic Information
ID: ALA4771279
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi (MHOM/CH/00/Tulahuen C2, lacZ) amastigotes infected in HFF-1 cells assessed as reduction in parasite growth incubated for 120 hrs by CPRG/Igepal substrate based photometric method
Organism: Trypanosoma cruzi
Strain: MHOM/CH/00/Tulahuen C2
Cell type: HFF-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4771279
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 361.40 | 3.31 | 3.31 |
| 347.37 | 3.00 | 3.00 |
| 217.18 | 2.29 | 2.29 |
| 381.82 | 3.66 | 3.66 |
| 395.42 | 4.32 | 4.32 |
| 407.43 | 3.02 | 3.02 |
| 426.27 | 3.77 | 3.77 |
| 356.40 | 2.89 | 2.89 |
| 308.34 | 3.49 | 3.49 |
| 401.22 | 3.97 | 3.97 |
| 422.40 | 2.92 | 2.92 |
| 377.40 | 3.01 | 3.01 |
| 279.30 | 2.88 | 2.88 |
| 392.37 | 2.91 | 2.91 |
| 413.39 | 3.42 | 3.42 |
| 422.40 | 2.92 | 2.92 |
| 312.76 | 4.14 | 4.14 |
| 312.76 | 4.14 | 4.14 |
| 330.32 | 2.85 | 2.85 |
| 365.36 | 3.14 | 3.14 |
| 333.35 | 2.61 | 2.61 |
| 411.85 | 3.67 | 3.67 |
| 359.39 | 3.41 | 3.41 |
| 308.34 | 3.49 | 3.49 |
| 426.27 | 3.77 | 3.77 |
| 387.44 | 4.21 | 4.21 |
| 377.40 | 3.01 | 3.01 |
| 330.75 | 4.28 | 4.28 |
| 312.76 | 4.14 | 4.14 |
| 392.37 | 2.91 | 2.91 |
| 304.35 | 3.82 | 3.82 |
| 431.37 | 3.90 | 3.90 |
| 353.33 | 3.40 | 3.40 |
| 323.31 | 3.39 | 3.39 |
| 466.34 | 4.98 | 4.98 |
| 172.19 | 2.38 | 2.38 |
| 296.30 | 3.62 | 3.62 |
| 202.21 | 2.39 | 2.39 |
| 368.39 | 3.51 | 3.51 |
| 376.33 | 4.51 | 4.51 |
| 381.82 | 3.66 | 3.66 |
| 314.29 | 3.76 | 3.76 |
| 438.28 | 4.17 | 4.17 |
| 303.32 | 3.36 | 3.36 |
| 437.37 | 2.82 | 2.82 |
| 278.31 | 3.48 | 3.48 |
| 323.31 | 3.39 | 3.39 |
| 426.82 | 3.57 | 3.57 |
| 279.30 | 2.88 | 2.88 |
| 258.32 | 3.30 | 3.30 |
| 357.21 | 4.25 | 4.25 |
| 416.26 | 4.31 | 4.31 |
| 323.31 | 3.39 | 3.39 |
| 409.44 | 4.18 | 4.18 |
| 333.35 | 3.36 | 3.36 |
| 381.82 | 3.66 | 3.66 |