Basic Information
ID: ALA4771537
Type: Binding
Description: Inhibition of TEL-fused EGFR L858R mutant (unknown origin) transfected in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell viability assay
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4771537
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 565.47 | 6.30 | 6.30 |
| 612.60 | 8.51 | 8.51 |
| 564.53 | 6.41 | 6.41 |
| 564.53 | 6.41 | 6.41 |
| 448.98 | 6.06 | 6.06 |
| 539.01 | 6.33 | 6.33 |
| 475.44 | 6.03 | 6.03 |
| 601.70 | 8.77 | 8.77 |
| 593.75 | 7.77 | 7.77 |
| 554.58 | 6.56 | 6.56 |
| 578.70 | 7.66 | 7.66 |
| 464.54 | 6.29 | 6.29 |
| 612.60 | 8.51 | 8.51 |
| 586.14 | 8.54 | 8.54 |