Inhibition of RIPK1 in human FADD-deficient Jurkat I 2.1 cells assessed as protection against TNFalpha-induced necroptosis measured after 24 hrs by MT...

Basic Information

ID: ALA4772126

Type: Binding

Description: Inhibition of RIPK1 in human FADD-deficient Jurkat I 2.1 cells assessed as protection against TNFalpha-induced necroptosis measured after 24 hrs by MTS assay

Format: BAO_0000221

Organism: Homo sapiens

Cell type: Jurkat I 2.1

Target: Receptor-interacting serine/threonine-protein kinase 1(ALA5464)

Document: ALA4765378

Inhibition of RIPK1 in human FADD-deficient Jurkat I 2.1 cells assessed as protection against TNFalpha-induced necroptosis measured after 24 hrs by MTS assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4772126

Inhibition

Total(57)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
210.24	2.94	2.94
268.16	3.54	3.54
294.20	4.07	4.07
234.26	2.68	2.68
279.26	3.09	3.09
299.25	3.12	3.12
213.28	2.76	2.76
257.30	1.75	1.75
220.23	2.29	2.29
262.31	3.46	3.46
290.37	4.24	4.24
236.23	1.53	1.53
271.39	4.50	4.50
236.23	1.53	1.53
260.30	3.22	3.22
273.34	3.09	3.09
267.33	3.67	3.67
218.22	2.07	2.07
282.26	2.72	2.72
264.24	1.45	1.45
249.74	3.96	3.96
214.63	2.86	2.86
263.26	1.02	1.02
291.31	1.80	1.80
336.44	3.75	3.75
260.30	3.22	3.22
254.25	3.21	3.21
350.47	4.14	4.14
206.21	1.90	1.90
336.15	4.56	4.56
333.14	3.98	3.98
247.30	2.56	2.56
310.36	4.35	4.35
268.28	3.08	3.08
229.33	3.62	3.62
282.30	3.57	3.57
251.31	3.42	3.42
247.30	2.56	2.56
295.39	4.45	4.45
240.10	2.76	2.76
234.26	2.68	2.68
285.47
322.41	3.70	3.70
315.16	3.38	3.38
271.75	4.32	4.32
216.20	1.52	1.52
346.44	4.08	4.08
251.31	3.42	3.42
234.26	2.54	2.54
220.23	2.29	2.29
254.25	3.21	3.21
297.32	3.28	3.28
220.23	2.29	2.29
322.25	4.23	4.23
268.28	3.08	3.08