Antagonist activity at human NPFFR1 expressed in CHO-RD-HGA16 cells assessed as reduction in NPFF-induced calcium influx by measuring apparent dissoci...

Basic Information

ID: ALA4772284

Type: Functional

Description: Antagonist activity at human NPFFR1 expressed in CHO-RD-HGA16 cells assessed as reduction in NPFF-induced calcium influx by measuring apparent dissociation constant Ke preincubated for 15 mins followed by NPFF addition by calcium-5 dye based fluorescence method

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO/Galpha16

Target:  Neuropeptide FF receptor 1(ALA5951)

Document:  ALA4765381

Antagonist activity at human NPFFR1 expressed in CHO-RD-HGA16 cells assessed as reduction in NPFF-induced calcium influx by measuring apparent dissociation constant Ke preincubated for 15 mins followed by NPFF addition by calcium-5 dye based fluorescence method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
524.024.784.78
445.004.814.81