Basic Information
ID: ALA4772333
Type: Binding
Description: Inhibition of Top1 in human MCF7 cells using supercoiled pBS (SK+) DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MCF7
Target: DNA topoisomerase I(ALA1781)
Document: ALA4765384
Inhibition of Top1 in human MCF7 cells using supercoiled pBS (SK+) DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4772333
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 421.45 | 1.85 | 1.85 |
| 426.48 | 4.66 | 4.66 |
| 410.48 | 4.96 | 4.96 |
| 412.45 | 4.36 | 4.36 |
| 414.44 | 4.79 | 4.79 |
| 421.46 | 4.52 | 4.52 |
| 396.45 | 4.65 | 4.65 |
| 429.52 | 4.86 | 4.86 |
| 411.47 | 4.23 | 4.23 |
| 425.49 | 5.26 | 5.26 |