Basic Information
ID: ALA4772593
Type: Binding
Description: Inverse agonist activity at human RORgammat assessed as maximal inhibition of N-terminal biotinylated co-activator SRC1 recruitment measured after 60 mins by FRET assay relative to agonist
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4772593
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.37 | 6.53 | 6.53 |
| 515.32 | 5.91 | 5.91 |
| 527.33 | 6.82 | 6.82 |
| 548.37 | 6.37 | 6.37 |
| 527.33 | 6.82 | 6.82 |
| 549.28 | 7.06 | 7.06 |
| 533.36 | 6.28 | 6.28 |
| 546.40 | 7.31 | 7.31 |
| 481.38 | 4.87 | 4.87 |
| 547.38 | 6.67 | 6.67 |
| 472.46 | 5.82 | 5.82 |
| 547.74 | 7.16 | 7.16 |
| 528.31 | 6.46 | 6.46 |
| 532.37 | 6.28 | 6.28 |
| 519.37 | 7.07 | 7.07 |
| 360.41 | 4.30 | 4.30 |
| 455.46 | 4.92 | 4.92 |
| 506.91 | 6.72 | 6.72 |
| 509.34 | 6.77 | 6.77 |
| 576.38 | 5.57 | 5.57 |
| 548.37 | 6.25 | 6.25 |
| 529.30 | 6.00 | 6.00 |
| 513.30 | 6.51 | 6.51 |
| 499.27 | 6.58 | 6.58 |
| 531.29 | 6.98 | 6.98 |
| 529.30 | 6.34 | 6.34 |
| 514.29 | 5.90 | 5.90 |
| 548.37 | 5.79 | 5.79 |
| 527.33 | 6.90 | 6.90 |
| 534.34 | 5.53 | 5.53 |
| 576.38 | 5.71 | 5.71 |
| 517.89 | 6.29 | 6.29 |
| 527.33 | 7.07 | 7.07 |
| 492.88 | 6.42 | 6.42 |
| 519.37 | 6.97 | 6.97 |
| 531.29 | 6.65 | 6.65 |
| 518.38 | 7.01 | 7.01 |
| 531.29 | 6.65 | 6.65 |