Basic Information
ID: ALA4773080
Type: Binding
Description: Antagonist activity at human NOD2 in HEK-Blue hNOD2 cells assessed as reduction in secreted alkaline phosphatase reporter activity at 10 uM preincubated for 3 hrs followed by stimulated with MDP for 20 hrs by Spectrophotometer method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-Blue hNOD2
Target: Nucleotide-binding oligomerization domain-containing protein 2(ALA1293266)
Document: ALA4765404
Antagonist activity at human NOD2 in HEK-Blue hNOD2 cells assessed as reduction in secreted alkaline phosphatase reporter activity at 10 uM preincubated for 3 hrs followed by stimulated with MDP for 20 hrs by Spectrophotometer method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4773080
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.44 | 5.56 | 5.56 |
| 375.47 | 1.73 | 1.73 |
| 493.51 | 4.87 | 4.87 |
| 595.64 | 5.99 | 5.99 |
| 455.50 | 4.99 | 4.99 |
| 415.51 | 3.92 | 3.92 |
| 455.50 | 5.11 | 5.11 |
| 426.49 | 3.49 | 3.49 |
| 467.47 | 4.54 | 4.54 |
| 391.45 | 3.21 | 3.21 |
| 337.44 | 2.96 | 2.96 |
| 484.50 | 4.14 | 4.14 |
| 524.61 | 5.72 | 5.72 |
| 412.39 | 2.78 | 2.78 |
| 435.93 | 4.27 | 4.27 |
| 469.48 | 4.63 | 4.63 |
| 503.93 | 5.29 | 5.29 |
| 489.90 | 4.98 | 4.98 |
| 555.57 | 5.28 | 5.28 |
| 387.50 | 3.97 | 3.97 |
| 413.37 | 3.37 | 3.37 |
| 483.51 | 4.68 | 4.68 |
| 395.48 | 2.85 | 2.85 |
| 515.51 | 4.34 | 4.34 |
| 401.48 | 3.61 | 3.61 |
| 427.40 | 3.46 | 3.46 |
| 461.97 | 4.67 | 4.67 |
| 355.41 | 2.54 | 2.54 |
| 493.51 | 4.87 | 4.87 |
| 469.48 | 4.63 | 4.63 |
| 483.51 | 4.94 | 4.94 |
| 487.47 | 4.77 | 4.77 |
| 468.50 | 4.21 | 4.21 |
| 351.42 | 2.49 | 2.49 |
| 339.41 | 2.32 | 2.32 |
| 325.43 | 2.79 | 2.79 |
| 469.48 | 4.63 | 4.63 |
| 488.49 | 4.93 | 4.93 |
| 297.38 | 2.06 | 2.06 |
| 469.48 | 4.63 | 4.63 |
| 311.40 | 2.40 | 2.40 |
| 479.96 | 4.81 | 4.81 |
| 515.51 | 4.34 | 4.34 |
| 487.47 | 4.77 | 4.77 |
| 353.48 | 3.57 | 3.57 |