Basic Information
ID: ALA4773361
Type: Toxicity
Description: Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for antileishmanial activity against Leishmania donovani MHOM/ET/67/L82 amastigotes
Activity Charts
Bioactivity
Activity Types for Assay ALA4773361
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.39 | 2.62 | 2.62 |
| 326.39 | 4.68 | 4.68 |
| 386.36 | 2.38 | 2.38 |
| 354.36 | 2.97 | 2.97 |
| 414.41 | 2.99 | 2.99 |
| 442.46 | 3.94 | 3.94 |
| 440.50 | 3.08 | 3.08 |
| 296.32 | 3.73 | 3.73 |
| 430.09 | 4.14 | 4.14 |
| 444.12 | 4.44 | 4.44 |
| 325.19 | 4.94 | 4.94 |
| 242.27 | 2.60 | 2.60 |
| 412.48 | 4.27 | 4.27 |
| 470.52 | 4.54 | 4.54 |
| 474.50 | 5.58 | 5.58 |
| 466.57 | 6.04 | 6.04 |
| 430.09 | 4.14 | 4.14 |
| 414.09 | 5.16 | 5.16 |
| 498.57 | 5.33 | 5.33 |
| 468.55 | 3.69 | 3.69 |
| 470.52 | 4.72 | 4.72 |
| 335.20 | 4.40 | 4.40 |
| 268.31 | 3.74 | 3.74 |
| 382.41 | 3.75 | 3.75 |
| 363.21 | 3.94 | 3.94 |
| 414.41 | 3.16 | 3.16 |
| 305.17 | 4.39 | 4.39 |
| 298.34 | 3.48 | 3.48 |
| 480.56 | 5.53 | 5.53 |
| 472.49 | 0.86 | 0.86 |
| 438.52 | 5.26 | 5.26 |
| 410.47 | 4.53 | 4.53 |
| 368.43 | 3.96 | 3.96 |
| 334.37 | 3.97 | 3.97 |
| 438.52 | 5.31 | 5.31 |
| 382.20 | 4.24 | 4.24 |
| 337.17 | 3.07 | 3.07 |
| 290.75 | 4.29 | 4.29 |
| 321.17 | 3.36 | 3.36 |
| 470.52 | 4.72 | 4.72 |
| 398.09 | 5.46 | 5.46 |
| 400.07 | 4.13 | 4.13 |
| 414.09 | 5.16 | 5.16 |
| 468.55 | 3.69 | 3.69 |
| 256.30 | 3.64 | 3.64 |
| 286.33 | 2.91 | 2.91 |
| 582.73 | 7.84 | 7.84 |
| 442.46 | 3.94 | 3.94 |
| 337.35 | 3.80 | 3.80 |
| 240.30 | 3.93 | 3.93 |
| 321.17 | 3.36 | 3.36 |
| 366.46 | 5.29 | 5.29 |
| 386.36 | 2.81 | 2.81 |
| 442.46 | 3.77 | 3.77 |
| 351.20 | 3.37 | 3.37 |
| 272.30 | 2.61 | 2.61 |
| 338.43 | 4.64 | 4.64 |
| 498.57 | 5.32 | 5.32 |
| 438.52 | 5.31 | 5.31 |
| 319.20 | 4.69 | 4.69 |
| 414.47 | 5.25 | 5.25 |
| 524.58 | 3.87 | 3.87 |
| 365.22 | 3.68 | 3.68 |
| 305.17 | 3.66 | 3.66 |
| 256.30 | 2.90 | 2.90 |
| 346.38 | 4.08 | 4.08 |
| 438.43 | 3.49 | 3.49 |
| 466.57 | 5.87 | 5.87 |
| 494.63 | 6.78 | 6.78 |
| 308.38 | 4.53 | 4.53 |
| 400.07 | 4.13 | 4.13 |