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Assay Report Card

Basic Information

ID: ALA4773458

Type: Functional

Description: Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced cytosolic calcium flux preincubated for 20 mins followed by CXCL12 addition by calcium 4 dye based FLIPR TETRA analysis

Organism: Homo sapiens

Cell type: T cell

Activity Charts

Bioactivity

Activity Types for Assay ALA4773458

IC50

Total(15)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
502.800.420.42
391.522.452.45
366.512.662.66
366.512.512.51
352.492.272.27
352.492.272.27
394.573.363.36
396.542.572.57
380.542.972.97
366.512.582.58
366.512.582.58
366.512.582.58
352.492.272.27
384.502.722.72
366.512.582.58
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