Basic Information
ID: ALA4773496
Type: Functional
Description: Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication at 0.8 uM supplemented with fresh medium containing compound every 2 days for 6 days by RT-PCR analysis relative to control
Format: BAO_0000218
Organism: Hepatitis B virus
Cell type: HepG2 2.2.15
Target: Hepatitis B virus(ALA613497)
Document: ALA4765418
Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication at 0.8 uM supplemented with fresh medium containing compound every 2 days for 6 days by RT-PCR analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4773496
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.26 | -0.59 | -0.59 |
| 451.62 | 4.74 | 4.74 |
| 503.67 | 5.47 | 5.47 |
| 493.63 | 5.06 | 5.06 |
| 449.58 | 4.66 | 4.66 |
| 465.58 | 4.28 | 4.28 |
| 535.67 | 5.26 | 5.26 |
| 435.55 | 4.27 | 4.27 |
| 517.65 | 4.89 | 4.89 |
| 475.61 | 4.69 | 4.69 |
| 459.62 | 5.07 | 5.07 |
| 545.71 | 5.67 | 5.67 |
| 473.64 | 5.46 | 5.46 |
| 489.64 | 5.08 | 5.08 |
| 479.60 | 4.67 | 4.67 |
| 521.64 | 4.87 | 4.87 |
| 445.59 | 4.68 | 4.68 |
| 537.71 | 5.34 | 5.34 |
| 507.61 | 4.48 | 4.48 |
| 495.67 | 5.14 | 5.14 |
| 463.60 | 5.05 | 5.05 |