Basic Information
ID: ALA4773503
Type: Functional
Description: Antiviral activity against lamivudine and entecavir-resistant HBV harboring rtL180 M/rtM204V/rtT184L mutant infected in human HepG2.2.15 cells assessed as inhibition of DNA replication at 10 uM supplemented with fresh medium containing compound every 2 days for 6 days by RT-PCR analysis relative to control
Organism: Hepatitis B virus
Cell type: HepG2 2.2.15
Activity Charts
Bioactivity
Activity Types for Assay ALA4773503
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.30 | -0.83 | -0.83 |