Basic Information
ID: ALA4774027
Type: Binding
Description: Inhibition of HDAC in human HeLa cell extracts assessed as inhibition of substrate deacetylation using Boc-Lys (q-Ac)-AMC as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4774027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 264.32 | 2.47 | 2.47 |
| 411.45 | 4.30 | 4.30 |
| 411.45 | 4.39 | 4.39 |
| 413.43 | 3.62 | 3.62 |
| 383.40 | 3.61 | 3.61 |
| 397.43 | 3.91 | 3.91 |
| 535.04 | 4.33 | 4.33 |
| 427.45 | 4.01 | 4.01 |
| 413.43 | 3.62 | 3.62 |
| 399.40 | 3.32 | 3.32 |
| 355.35 | 2.83 | 2.83 |
| 521.01 | 3.94 | 3.94 |
| 425.48 | 4.69 | 4.69 |
| 562.06 | 3.24 | 3.24 |
| 397.43 | 4.00 | 4.00 |
| 441.48 | 4.40 | 4.40 |
| 549.06 | 4.72 | 4.72 |
| 327.29 | 2.05 | 2.05 |
| 427.45 | 4.10 | 4.10 |
| 547.05 | 4.47 | 4.47 |
| 535.04 | 4.33 | 4.33 |
| 427.45 | 4.01 | 4.01 |
| 549.02 | 3.32 | 3.32 |
| 413.43 | 3.71 | 3.71 |
| 441.48 | 4.40 | 4.40 |
| 533.02 | 4.08 | 4.08 |
| 369.37 | 3.22 | 3.22 |
| 506.98 | 3.55 | 3.55 |
| 521.01 | 3.94 | 3.94 |