Basic Information
ID: ALA4774177
Type: Binding
Description: Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compound addition and measured after 24 hrs by ELISA
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4774177
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.28 | 3.91 | 3.91 |
| 438.48 | 3.76 | 3.76 |
| 311.29 | 3.56 | 3.56 |
| 325.32 | 3.57 | 3.57 |
| 452.51 | 4.15 | 4.15 |
| 487.53 | 2.12 | 2.12 |
| 367.40 | 4.84 | 4.84 |
| 424.45 | 3.37 | 3.37 |
| 297.26 | 3.55 | 3.55 |
| 488.52 | 2.55 | 2.55 |