Basic Information
ID: ALA4774180
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-HIS6 fused RET V804M mutant (658 to 1114 residues) expressed in Sf9 insect cells using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 60 mins followed by substrate addition by microfluidic assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Tyrosine-protein kinase receptor RET(ALA2041)
Document: ALA4765434
Inhibition of recombinant human N-terminal GST-HIS6 fused RET V804M mutant (658 to 1114 residues) expressed in Sf9 insect cells using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 60 mins followed by substrate addition by microfluidic assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4774180
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.54 | 4.57 | 4.57 |
| 483.58 | 4.31 | 4.31 |
| 544.64 | 5.24 | 5.24 |