Basic Information
ID: ALA4774283
Type: Binding
Description: Selectivity index, ratio of IC50 for CXCR2 (unknown origin) expressed in U2OS cells cotransfected with beta-arrestin/TEV protease fusion protein and beta-lactamase to IC50 for CXCR4 (unknown origin) expressed in U2OS cells cotransfected with beta-arrestin/TEV protease fusion protein and beta-lactamase
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4765436
Selectivity index, ratio of IC50 for CXCR2 (unknown origin) expressed in U2OS cells cotransfected with beta-arrestin/TEV protease fusion protein and beta-lactamase to IC50 for CXCR4 (unknown origin) expressed in U2OS cells cotransfected with beta-arrestin/TEV protease fusion protein and beta-lactamase: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4774283
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.52 | 4.72 | 4.72 |
| 390.53 | 4.88 | 4.88 |
| 388.56 | 5.39 | 5.39 |
| 346.48 | 4.70 | 4.70 |
| 434.58 | 5.19 | 5.19 |
| 462.64 | 5.97 | 5.97 |
| 417.60 | 5.24 | 5.24 |
| 388.56 | 4.85 | 4.85 |
| 374.53 | 5.17 | 5.17 |
| 392.52 | 5.31 | 5.31 |
| 421.59 | 6.25 | 6.25 |
| 432.61 | 5.96 | 5.96 |
| 450.58 | 4.60 | 4.60 |
| 402.59 | 5.95 | 5.95 |
| 388.56 | 5.56 | 5.56 |
| 418.58 | 4.82 | 4.82 |
| 454.52 | 5.50 | 5.50 |
| 390.53 | 4.59 | 4.59 |
| 474.69 | 7.13 | 7.13 |
| 458.53 | 6.07 | 6.07 |
| 442.53 | 6.19 | 6.19 |
| 390.53 | 4.84 | 4.84 |
| 404.56 | 5.18 | 5.18 |
| 392.52 | 5.31 | 5.31 |
| 435.62 | 5.93 | 5.93 |
| 418.58 | 4.82 | 4.82 |
| 430.64 | 6.47 | 6.47 |
| 404.56 | 5.15 | 5.15 |
| 389.55 | 4.16 | 4.16 |
| 370.50 | 3.81 | 3.81 |
| 404.56 | 5.18 | 5.18 |
| 474.53 | 5.48 | 5.48 |
| 486.58 | 6.85 | 6.85 |