Basic Information
ID: ALA4774375
Type: Binding
Description: Inhibition of recombinant human SIRT1 (133 to 747 residues) expressed in Escherichia coli BL21(DE3) at 50 uM using ZMAL as substrate incubated for 4 hrs in presence of NAD+ followed by incubation with trypsin for 20 mins by trypsin-coupled assay based homogenous fluorescence analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4774375
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 122.13 | 0.18 | 0.18 |
| 357.32 | 2.71 | 2.71 |
| 1297.30 | ||
| 313.31 | 3.01 | 3.01 |
| 341.32 | 3.00 | 3.00 |
| 343.34 | 3.07 | 3.07 |
| 297.31 | 3.31 | 3.31 |