Basic Information
ID: ALA4774607
Type: Binding
Description: Inhibition of P-gp in vincristine-resistant human CEM cells at 0.1 to 1 uM using calcein-AM as substrate preincubated for 30 mins followed by compound washout and subsequent substrate addition measured after 60 mins by flow cytometric analysis
Organism: Homo sapiens
Cell type: CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4774607
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 622.76 | 7.16 | 7.16 |
| 592.74 | 7.15 | 7.15 |
| 627.18 | 7.81 | 7.81 |
| 558.72 | 6.37 | 6.37 |
| 676.73 | 8.05 | 8.05 |
| 598.77 | 7.22 | 7.22 |