Basic Information
ID: ALA4774696
Type: Functional
Description: Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium release incubated for 40 mins by Fluo-4AM dye based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Alpha-1d adrenergic receptor(ALA223)
Document: ALA4765451
Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium release incubated for 40 mins by Fluo-4AM dye based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4774696
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.52 | 2.34 | 2.34 |
| 463.62 | 5.05 | 5.05 |
| 468.04 | 5.69 | 5.69 |
| 449.60 | 4.66 | 4.66 |
| 454.01 | 5.30 | 5.30 |
| 435.57 | 4.27 | 4.27 |