Basic Information
ID: ALA4774996
Type: Binding
Description: Inverse agonist activity at human LXRbeta transfected in human HEK293T cells co-transfected with pSG5 and pGL3/(DR-4)-c-fos-FF-luc/pCMV/Renilla-luc assessed as receptor transactivation incubated for 20 hrs by dual luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4774996
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 595.74 | 5.84 | 5.84 |
| 535.69 | 7.43 | 7.43 |
| 594.18 | 6.09 | 6.09 |
| 586.18 | 7.32 | 7.32 |
| 603.23 | 7.03 | 7.03 |
| 397.52 | 4.24 | 4.24 |
| 512.65 | 6.43 | 6.43 |
| 590.74 | 5.83 | 5.83 |
| 464.56 | 5.05 | 5.05 |
| 604.73 | 6.04 | 6.04 |
| 436.55 | 4.76 | 4.76 |
| 406.95 | 4.57 | 4.57 |
| 416.52 | 3.80 | 3.80 |
| 547.10 | 7.08 | 7.08 |
| 590.74 | 5.83 | 5.83 |
| 586.63 | 4.98 | 4.98 |
| 588.15 | 7.29 | 7.29 |
| 588.77 | 5.86 | 5.86 |
| 542.65 | 4.46 | 4.46 |
| 514.64 | 4.16 | 4.16 |
| 574.74 | 5.47 | 5.47 |
| 572.15 | 6.93 | 6.93 |