Basic Information
ID: ALA4775171
Type: Functional
Description: Antagonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP accumulation by cAMP split-luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Melanocortin receptor 4(ALA259)
Document: ALA4765463
Antagonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP accumulation by cAMP split-luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775171
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1074.26 | ||
| 1075.25 | ||
| 1108.70 | ||
| 1110.33 | ||
| 1050.23 | ||
| 1158.33 | ||
| 1110.33 | ||
| 1088.32 | ||
| 1092.25 | ||
| 1034.23 | ||
| 1075.25 | ||
| 1098.28 | ||
| 1108.70 | ||
| 1098.28 | ||
| 1092.25 | ||
| 1122.30 | ||
| 1114.32 | ||
| 1092.25 | ||
| 1108.27 | ||
| 1088.29 | ||
| 1108.70 |