Inhibition of NLRP3 inflammasome activation in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta secretion at 5 to 15 uM pre-treated ...

ID: ALA4775291

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta secretion at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and nigericin for 1 hr by ELISA analysis

Format: BAO_0000221

Organism: Homo sapiens

Cell type: THP-1

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA4765468

Inhibition of NLRP3 inflammasome activation in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta secretion at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and nigericin for 1 hr by ELISA analysis: 1