Basic Information
ID: ALA4775292
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in PMA-stimulated mouse BMDM cells assessed as reduction in IL-1beta secretion at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by ELISA analysis
Format: BAO_0000221
Organism: Mus musculus
Cell type: BMDM
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA4765468
Inhibition of NLRP3 inflammasome activation in PMA-stimulated mouse BMDM cells assessed as reduction in IL-1beta secretion at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by ELISA analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775292
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.70 | 3.39 | 3.39 |