Inhibition of NLRP3 in PMA-stimulated human THP-1 cells assessed as reduction in ATP-induced interaction between ASC and NLRP3 at 15 to 45 uM pre-trea...

ID: ALA4775312

Type: Binding

Description: Inhibition of NLRP3 in PMA-stimulated human THP-1 cells assessed as reduction in ATP-induced interaction between ASC and NLRP3 at 15 to 45 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by Co-IP and Western blot analysis

Format: BAO_0000221

Organism: Homo sapiens

Cell type: THP-1

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA4765468

Inhibition of NLRP3 in PMA-stimulated human THP-1 cells assessed as reduction in ATP-induced interaction between ASC and NLRP3 at 15 to 45 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by Co-IP and Western blot analysis: 1