Basic Information
ID: ALA4775313
Type: Binding
Description: Inhibition of NLRC4 in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and Salmonella typhimurium flagellin for 1 hr by ELISA analysis
Format: BAO_0000221
Organism: Homo sapiens
Cell type: THP-1
Target: NLR family CARD domain-containing protein 4(ALA4630857)
Document: ALA4765468
Inhibition of NLRC4 in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and Salmonella typhimurium flagellin for 1 hr by ELISA analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775313
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.70 | 3.39 | 3.39 |