Assay Report Card

Basic Information

ID: ALA4775314

Type: Binding

Description: Inhibition of AIM2 in PMA-stimulated human THP-1 cells transfected with poly(dA:dT) assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 4 hrs by ELISA analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
590.703.393.39