Basic Information
ID: ALA4775314
Type: Binding
Description: Inhibition of AIM2 in PMA-stimulated human THP-1 cells transfected with poly(dA:dT) assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 4 hrs by ELISA analysis
Format: BAO_0000221
Organism: Homo sapiens
Cell type: THP-1
Target: Interferon-inducible protein AIM2(ALA4630802)
Document: ALA4765468
Inhibition of AIM2 in PMA-stimulated human THP-1 cells transfected with poly(dA:dT) assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 4 hrs by ELISA analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775314
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.70 | 3.39 | 3.39 |