Assay Report Card

Basic Information

ID: ALA4775317

Type: Functional

Description: Inhibition of ATP-induced mitochondrial membrane potential loss in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta release at 30 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by Mito-tracker Red dye based confocal microscopy

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
590.703.393.39