Basic Information
ID: ALA4775318
Type: Functional
Description: Inhibition of ATP-induced ROS production in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta release at 30 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by MitoSOX dye based confocal microscopy
Format: BAO_0000221
Organism: Homo sapiens
Cell type: THP-1
Target: Unchecked(ALA612545)
Document: ALA4765468
Inhibition of ATP-induced ROS production in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta release at 30 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and ATP for 1 hr by MitoSOX dye based confocal microscopy: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775318
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.70 | 3.39 | 3.39 |