Basic Information
ID: ALA4775324
Type: Functional
Description: Protective activity against DSS-induced inflammasome activation in CS7BL/6 mouse model of DSS-induced acute ulcerative colitis assessed as reduction in NLRP3 protein expression in colon tissue at 40 to 80 mg/kg, po dosed via gavage from day 1 to day 10 by immunohistochemistry analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: CS7BL/6
Target: Mus musculus(ALA375)
Document: ALA4765468
Protective activity against DSS-induced inflammasome activation in CS7BL/6 mouse model of DSS-induced acute ulcerative colitis assessed as reduction in NLRP3 protein expression in colon tissue at 40 to 80 mg/kg, po dosed via gavage from day 1 to day 10 by immunohistochemistry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775324
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.70 | 3.39 | 3.39 |