Assay Report Card

Basic Information

ID: ALA4775325

Type: Functional

Description: Protective activity against DSS-induced inflammasome activation in CS7BL/6 mouse model of DSS-induced acute ulcerative colitis assessed as reduction in IL-1beta protein expression in colon tissue at 40 to 80 mg/kg, po dosed via gavage from day 1 to day 10 by immunohistochemistry analysis

Organism: Mus musculus

Strain: CS7BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
590.703.393.39