Potency index, ratio of EC50 for 1-alpha,25-(OH)2D3 to EC50 for test compound for agonist activity at VDR in human HL60 cells assessed as induction of...

Basic Information

ID: ALA4775516

Type: Binding

Description: Potency index, ratio of EC50 for 1-alpha,25-(OH)2D3 to EC50 for test compound for agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reduction assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HL-60

Target:  Vitamin D receptor(ALA1977)

Document:  ALA4765478

Potency index, ratio of EC50 for 1-alpha,25-(OH)2D3 to EC50 for test compound for agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reduction assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
432.696.926.92