Basic Information
ID: ALA4775528
Type: Binding
Description: Inhibition of TYK2 in IFN-alpha stimulated human Kit225 T cells by luciferase reporter gene assay
Format: BAO_0000221
Organism: Homo sapiens
Cell type: KIT225
Target: Tyrosine-protein kinase TYK2(ALA3553)
Document: ALA4765480
Inhibition of TYK2 in IFN-alpha stimulated human Kit225 T cells by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4775528
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.47 | 1.73 | 1.73 |
| 452.49 | 2.40 | 2.40 |
| 534.51 | 3.16 | 3.16 |
| 493.54 | 2.10 | 2.10 |
| 422.46 | 2.39 | 2.39 |
| 436.49 | 2.70 | 2.70 |
| 435.50 | 3.31 | 3.31 |
| 451.50 | 3.01 | 3.01 |
| 422.46 | 2.39 | 2.39 |
| 440.45 | 2.53 | 2.53 |
| 498.53 | 2.76 | 2.76 |
| 492.55 | 2.70 | 2.70 |
| 436.49 | 2.70 | 2.70 |
| 422.46 | 2.39 | 2.39 |
| 421.48 | 3.00 | 3.00 |
| 439.47 | 3.14 | 3.14 |
| 480.54 | 2.62 | 2.62 |
| 493.54 | 2.10 | 2.10 |
| 511.53 | 2.23 | 2.23 |
| 439.47 | 3.14 | 3.14 |
| 493.54 | 2.10 | 2.10 |
| 479.56 | 3.23 | 3.23 |
| 480.54 | 2.62 | 2.62 |
| 452.49 | 2.40 | 2.40 |
| 422.46 | 2.39 | 2.39 |
| 480.54 | 2.62 | 2.62 |
| 421.48 | 3.00 | 3.00 |
| 521.60 | 2.88 | 2.88 |