Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation

Basic Information

ID: ALA4775529

Type: Binding

Description: Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation

Format: BAO_0000221

Organism: Homo sapiens

Tissue: Blood

Target:  Tyrosine-protein kinase TYK2(ALA3553)

Document:  ALA4765480

Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
425.471.731.73
452.492.402.40
534.513.163.16
493.542.102.10
422.462.392.39
436.492.702.70
435.503.313.31
451.503.013.01
422.462.392.39
440.452.532.53
498.532.762.76
492.552.702.70
436.492.702.70
422.462.392.39
421.483.003.00
439.473.143.14
480.542.622.62
493.542.102.10
511.532.232.23
439.473.143.14
493.542.102.10
479.563.233.23
480.542.622.62
452.492.402.40
422.462.392.39
480.542.622.62
421.483.003.00
521.602.882.88