Basic Information
ID: ALA4775718
Type: Unassigned
Description: Selectivity index, ratio of Cmax in DBA/J mouse model of CFA and glucose-6-phosphate isomerase-induced arthritis model at 10 mg/kg, po BID beginning 1 hr prior to GPI immunization and measured up to day 17 after GPI immunization by HPLC-MS/MS analysis to EC50 for inhibition of TNFalpha in mouse L929 cells exposed to compound incubated for 1 hr with mouse TNFalpha by luminescence based assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4775718
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.56 | 2.61 | 2.61 |