Basic Information
ID: ALA4805243
Type: Binding
Description: Inhibition of CDK8/CDK19 in TNF-alpha-induced HEK293 cells assessed as inhibition of CXCL1 expression as percent of control at 1 uM by QPCR assay relative to control
Format: BAO_0000221
Organism: Homo sapiens
Cell type: HEK293
Target: Cyclin-dependent kinase 8/19(ALA3885556)
Document: ALA4804282
Inhibition of CDK8/CDK19 in TNF-alpha-induced HEK293 cells assessed as inhibition of CXCL1 expression as percent of control at 1 uM by QPCR assay relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4805243
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.33 | 3.16 | 3.16 |
| 259.31 | 3.72 | 3.72 |
| 273.34 | 3.76 | 3.76 |
| 211.27 | 2.93 | 2.93 |
| 211.27 | 2.93 | 2.93 |