Basic Information
ID: ALA4807194
Type: Functional
Description: Inverse agonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4807194
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.57 | 3.79 | 3.79 |
| 385.46 | 4.78 | 4.78 |
| 327.38 | 3.99 | 3.99 |
| 385.42 | 3.76 | 3.76 |
| 361.83 | 4.64 | 4.64 |
| 378.45 | 3.03 | 3.03 |
| 411.38 | 4.89 | 4.89 |
| 403.48 | 5.66 | 5.66 |
| 328.37 | 3.38 | 3.38 |
| 399.49 | 5.17 | 5.17 |
| 419.48 | 5.78 | 5.78 |
| 380.42 | 3.00 | 3.00 |
| 462.55 | 3.54 | 3.54 |
| 383.45 | 4.55 | 4.55 |
| 462.55 | 3.48 | 3.48 |
| 372.38 | 3.90 | 3.90 |
| 378.45 | 3.17 | 3.17 |
| 411.50 | 5.31 | 5.31 |
| 343.38 | 3.69 | 3.69 |
| 364.42 | 2.78 | 2.78 |
| 385.46 | 4.78 | 4.78 |
| 364.42 | 2.64 | 2.64 |
| 406.50 | 3.81 | 3.81 |
| 394.45 | 3.25 | 3.25 |
| 372.42 | 3.78 | 3.78 |
| 427.54 | 5.95 | 5.95 |
| 432.52 | 3.99 | 3.99 |
| 410.47 | 4.11 | 4.11 |
| 392.48 | 3.42 | 3.42 |
| 373.41 | 3.70 | 3.70 |
| 387.44 | 3.36 | 3.36 |
| 357.41 | 4.00 | 4.00 |
| 369.46 | 5.11 | 5.11 |
| 357.41 | 4.00 | 4.00 |
| 355.44 | 4.55 | 4.55 |
| 282.34 | 4.29 | 4.29 |
| 405.48 | 3.39 | 3.39 |
| 356.43 | 3.95 | 3.95 |
| 371.44 | 4.39 | 4.39 |
| 345.37 | 4.13 | 4.13 |
| 409.45 | 4.35 | 4.35 |
| 412.46 | 3.69 | 3.69 |
| 394.45 | 3.39 | 3.39 |
| 415.49 | 4.79 | 4.79 |
| 371.44 | 4.39 | 4.39 |
| 328.37 | 3.38 | 3.38 |
| 393.39 | 4.59 | 4.59 |
| 350.39 | 2.39 | 2.39 |
| 448.52 | 3.24 | 3.24 |
| 399.49 | 5.17 | 5.17 |