Basic Information
ID: ALA4807218
Type: Binding
Description: Inhibition of human recombinant full length GST-tagged Wee1 expressed in baculovirus expression system using fluorescent-PolyGT substrate preincubated with enzyme for 10 mins followed by incubation with substrate and ATP for 1 hr by LanthaScreen Terbium Labeled TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase WEE1(ALA5491)
Document: ALA4806961
Inhibition of human recombinant full length GST-tagged Wee1 expressed in baculovirus expression system using fluorescent-PolyGT substrate preincubated with enzyme for 10 mins followed by incubation with substrate and ATP for 1 hr by LanthaScreen Terbium Labeled TR-FRET assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4807218
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.57 | 3.89 | 3.89 |
| 465.51 | 3.73 | 3.73 |
| 463.52 | 2.75 | 2.75 |
| 466.55 | 3.50 | 3.50 |
| 480.58 | 3.68 | 3.68 |
| 463.52 | 2.75 | 2.75 |
| 479.54 | 4.29 | 4.29 |
| 500.58 | 4.06 | 4.06 |
| 506.49 | 3.48 | 3.48 |
| 466.55 | 3.50 | 3.50 |
| 505.60 | 4.05 | 4.05 |
| 503.58 | 3.80 | 3.80 |
| 498.06 | 4.96 | 4.96 |
| 459.53 | 3.39 | 3.39 |
| 486.56 | 3.89 | 3.89 |
| 452.52 | 2.94 | 2.94 |
| 505.57 | 4.78 | 4.78 |
| 466.55 | 3.50 | 3.50 |
| 494.60 | 4.24 | 4.24 |
| 480.58 | 3.68 | 3.68 |
| 473.56 | 3.95 | 3.95 |
| 478.56 | 3.43 | 3.43 |
| 479.54 | 4.29 | 4.29 |
| 486.56 | 3.89 | 3.89 |
| 477.54 | 3.31 | 3.31 |
| 477.54 | 3.31 | 3.31 |
| 447.57 | 3.89 | 3.89 |
| 452.52 | 2.94 | 2.94 |
| 477.52 | 4.05 | 4.05 |
| 480.58 | 3.68 | 3.68 |