Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells after 7...

Basic Information

ID: ALA4807291

Type: Functional

Description: Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells after 7 days by flow cytometric analysis

Format: BAO_0000221

Organism: Homo sapiens

Cell type: PBMC

Target:  Probable G-protein coupled receptor 174(ALA3562167)

Document:  ALA4806962

Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells after 7 days by flow cytometric analysis: 38

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.553.483.48