Assay Report Card

Basic Information

ID: ALA4807293

Type: Functional

Description: Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells at 30 uM after 7 days by flow cytometric analysis

Organism: Homo sapiens

Cell type: PBMC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.553.483.48