ID: ALA4807293
Type: Functional
Description: Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells at 30 uM after 7 days by flow cytometric analysis
Format: BAO_0000221
Organism: Homo sapiens
Cell type: PBMC
Target: Probable G-protein coupled receptor 174(ALA3562167)
Document: ALA4806962
Inverse agonist activity at GPR174 in anti-CD3/CD28-stimulated human PBMCs assessed as reduction in FoxP3-positive Helios-positive nTreg cells at 30 uM after 7 days by flow cytometric analysis: 38
Bioactivity
Activity Types for Assay ALA4807293
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
462.55 | 3.48 | 3.48 |