Basic Information
ID: ALA4808123
Type: Functional
Description: Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 50 uM of obeticholic acid by HTRF assay
Organism: Homo sapiens
Cell type: HEK
Activity Charts
Bioactivity
Activity Types for Assay ALA4808123
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.15 | 4.14 | 4.14 |
| 297.14 | 4.27 | 4.27 |
| 331.68 | 4.03 | 4.03 |
| 315.13 | 4.41 | 4.41 |
| 328.26 | 4.43 | 4.43 |
| 348.68 | 4.78 | 4.78 |
| 324.30 | 4.60 | 4.60 |
| 359.73 | 4.59 | 4.59 |
| 330.69 | 4.64 | 4.64 |
| 331.58 | 4.92 | 4.92 |
| 348.68 | 4.78 | 4.78 |
| 298.12 | 3.67 | 3.67 |
| 355.61 | 4.41 | 4.41 |
| 348.68 | 4.78 | 4.78 |
| 344.72 | 4.94 | 4.94 |
| 331.68 | 4.03 | 4.03 |
| 355.70 | 4.51 | 4.51 |