Basic Information
ID: ALA4808127
Type: Functional
Description: Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of BAR-502 by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK
Target: Mas-related G-protein coupled receptor member X4(ALA4523430)
Document: ALA4806969
Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of BAR-502 by HTRF assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4808127
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.14 | 4.27 | 4.27 |
| 331.68 | 4.03 | 4.03 |
| 348.68 | 4.78 | 4.78 |
| 359.73 | 4.59 | 4.59 |
| 331.58 | 4.92 | 4.92 |
| 335.28 | 4.16 | 4.16 |
| 348.68 | 4.78 | 4.78 |
| 331.68 | 4.03 | 4.03 |