Basic Information
ID: ALA4808136
Type: Binding
Description: PROTAC activity at CRBN/CDK12 in human Jurkat cells assessed as induction of CDK12 degradation at 100 nM incubated for 6 hrs by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: Cereblon/Cyclin-dependent kinase 12(ALA4879535)
Document: ALA4806970
PROTAC activity at CRBN/CDK12 in human Jurkat cells assessed as induction of CDK12 degradation at 100 nM incubated for 6 hrs by western blot analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4808136
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 755.28 | 4.70 | 4.70 |
| 915.45 | 4.88 | 4.88 |
| 817.30 | 2.80 | 2.80 |
| 1020.81 | ||
| 852.39 | 4.55 | 4.55 |
| 741.25 | 4.31 | 4.31 |
| 887.40 | 4.10 | 4.10 |
| 837.40 | 4.48 | 4.48 |
| 1040.75 | ||
| 866.42 | 4.94 | 4.94 |