Basic Information
ID: ALA4808137
Type: Binding
Description: PROTAC activity at CRBN/CDK12 in human Jurkat cells assessed as induction of CDK12 degradation up to 500 nM incubated for 6 hrs by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: Cereblon/Cyclin-dependent kinase 12(ALA4879535)
Document: ALA4806970
PROTAC activity at CRBN/CDK12 in human Jurkat cells assessed as induction of CDK12 degradation up to 500 nM incubated for 6 hrs by western blot analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4808137
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 727.22 | 3.92 | 3.92 |
| 713.20 | 3.53 | 3.53 |
| 755.23 | 3.84 | 3.84 |
| 1020.81 | ||
| 801.26 | 2.70 | 2.70 |
| 943.51 | 5.66 | 5.66 |
| 773.25 | 2.78 | 2.78 |