Basic Information
ID: ALA4808301
Type: Functional
Description: Agonist activity at human APJ receptor expressed in HEK293T cells co-expressing PDZ-Rho-Gef-RLucll and rGFP-CAAX assessed as induction of recruitment of Galpha12 to cell membrane using coelenterazine luciferase substrate incubated for 5 mins by BRET assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4808301
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1550.86 | ||
| 1621.91 | ||
| 1627.92 | ||
| 1758.15 | ||
| 1706.03 | ||
| 1634.91 | ||
| 1577.86 | ||
| 1655.97 | ||
| 1529.82 | ||
| 1633.92 | ||
| 1527.80 | ||
| 1627.92 | ||
| 1543.84 | ||
| 1591.89 | ||
| 1668.03 | ||
| 1641.95 | ||
| 1591.89 | ||
| 1690.03 | ||
| 1571.85 | ||
| 1527.80 | ||
| 1616.90 | ||
| 1621.91 | ||
| 1623.89 | ||
| 1591.89 | ||
| 1635.94 | ||
| 1666.96 | ||
| 1615.91 | ||
| 1627.92 | ||
| 1768.15 | ||
| 1605.91 | ||
| 1621.91 | ||
| 1604.89 | ||
| 1591.89 | ||
| 1635.94 |