Basic Information
ID: ALA4808435
Type: Binding
Description: Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellular target engagement assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Protein arginine N-methyltransferase 5(ALA1795116)
Document: ALA4808168
Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellular target engagement assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4808435
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.41 | 3.21 | 3.21 |
| 466.93 | 2.44 | 2.44 |
| 462.53 | 2.90 | 2.90 |
| 449.49 | 2.65 | 2.65 |
| 536.43 | 3.84 | 3.84 |
| 525.41 | 2.86 | 2.86 |
| 468.46 | 2.06 | 2.06 |
| 511.38 | 2.55 | 2.55 |
| 447.51 | 3.31 | 3.31 |
| 525.41 | 3.01 | 3.01 |
| 468.90 | 2.03 | 2.03 |
| 446.51 | 2.09 | 2.09 |
| 527.38 | 2.60 | 2.60 |
| 466.49 | 2.73 | 2.73 |
| 452.45 | 1.51 | 1.51 |
| 450.47 | 1.93 | 1.93 |
| 484.48 | 2.87 | 2.87 |
| 513.35 | 2.14 | 2.14 |
| 447.51 | 3.31 | 3.31 |
| 431.50 | 2.51 | 2.51 |
| 498.34 | 2.56 | 2.56 |
| 513.35 | 2.14 | 2.14 |
| 463.97 | 3.83 | 3.83 |
| 451.46 | 2.24 | 2.24 |
| 512.36 | 2.86 | 2.86 |
| 508.42 | 3.94 | 3.94 |
| 467.91 | 2.75 | 2.75 |
| 465.94 | 3.17 | 3.17 |
| 462.53 | 2.90 | 2.90 |
| 468.46 | 2.06 | 2.06 |
| 465.94 | 3.17 | 3.17 |
| 510.39 | 3.27 | 3.27 |
| 468.46 | 2.06 | 2.06 |