Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...

Basic Information

ID: ALA4808479

Type: ADME

Description: Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Cytochrome P450 2C19(ALA3622)

Document: ALA4808169

Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4808479

IC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
305.34	0.45	0.45

Parent Molecular Weight

ALogP

Polar Surface Area

305.34

0.45

Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...

Basic Information

Activity Charts

Compound Summary